D-10 | Model Validation of Procedural Risk in Congenital Cardiac Catheterization (PREDIC3T) in the CCISC Registry

Procedural risk in Congenital Cardiac Catheterization (PREDIC3T) was recently reported as the contemporary procedure-type metric by C3PO (Congenital Project on Outcomes) registry. This has not been validated elsewhere. CCISC Cardiovascular Interventional Study Consortium) prospective catheterization registry dataset analyzed. The study period 14 years (2009 – 2022). primary outcome significant adverse event (SAE). Cases were assigned to 6 PREDIC3T categories. Univariate and multivariable logistic regression models used evaluate association between outcome. model discriminative performance evaluated c-statistic. In a total of 64,419 enrolled cases, case types 59,822 cases (93%). frequency for category 0=7,494 (13%), 1=16,932 (28%), 2=17,023 (29%), 3=9,885 (17%), 4=4,403 (7%), 5=4,085 (7%). SAE observed 2,474 (4.1%). rates 0=1.0%, 1=2.3%, 2=4.0%, 3=6.2%, 4=8.2%, 5=9.0%. model, type (odds ratios category: 0=0.49, 1=1.00, 2=1.40, 3=2.06, 4=2.79, 5=3.15; p<0.001) significantly associated with (c-statistic 0.707) after adjusting age, pre-procedural inotropic support systemic illness, low saturation, high pulmonary vascular resistance use general anesthesia. appeared be useful procedural classification tool.